Ph.D. Dissertation Defense by Steven Michael Herchko
DEVELOPMENT OF A MINIBEAM DELIVERY SYSTEM FOR USE WITH A RADIATION THERAPY RESEARCH PLATFORM
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Spatially fractionated radiation therapy (SFRT) utilizes multiple radiation beams to
combine areas of low and high dose within the treatment volume. Organ at risk (OAR)
tolerance with SFRT is greater than traditional techniques, with increasing benefits as the
beam size decreases. Minibeam radiation therapy (MBRT) is a form of SFRT with beam
sizes on the order of 1 mm, which is achievable utilizing conventional treatment techniques,